Zodiac Spot On Plus flea and tick control for cats is a long-lasting, once-a-month topical that stops the flea life cycle and helps prevent reinfestation. Zodiac Spot On for cats kills fleas, flea eggs, deer ticks and mosquitoes for up to 1 month. Contains 40% etofenprox and 3.6% s-methoprene, an insect growth regulator. Also contains a natural coat conditioner. For cats and kittens 12 weeks of age or older. Apply 1 tube at the back of the neck at base of head. Do not bathe within 24 hours of application. Do not apply more than once every month.